化学
过氧化物酶
抗菌活性
组合化学
X射线光电子能谱
细菌
核化学
酶
纳米技术
生物化学
化学工程
遗传学
生物
工程类
材料科学
作者
Jingfang Song,Jian He,Lin Yang,Weiguo Wang,Qinqin Bai,Feng Wei,Ranhui Li
摘要
To inhibit the growth of bacteria, the DA-PPI nanozyme with enhanced peroxidase-like activity was synthesized. The DA-PPI nanozyme was obtained by depositing high-affinity element iridium (Ir) on the surface of Pd-Pt dendritic structures. The morphology and composition of DA-PPI nanozyme were characterized using SEM, TEM, and XPS. The kinetic results showed that the DA-PPI nanozyme possessed a higher peroxidase-like activity than that of Pd-Pt dendritic structures. The PL, ESR, and DFT were employed to explain the high peroxidase activity. As a proof of concept, the DA-PPI nanozyme could effectively inhibit E. coli (G−) and S. aureus (G+) due to its high peroxidase-like activity. The study provides a new idea for the design of high active nanozymes and their application in the field of antibacterial.
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