化学
钯
催化作用
醌
联轴节(管道)
级联
组合化学
功能群
计算化学
有机化学
立体化学
材料科学
聚合物
色谱法
冶金
作者
Bijoy Debnath,Tanumay Sarkar,Pallab Karjee,Siddhartha K. Purkayastha,Ankur K. Guha,Tharmalingam Punniyamurthy
标识
DOI:10.1021/acs.joc.3c00173
摘要
Pd-catalyzed annulative coupling of spirovinylcyclopropyl oxindoles with p-quinone methides has been accomplished via cascade carbon-carbon bond formation to afford bis-spirooxindole scaffolds. The mild reaction conditions, diastereoselectivity, functional group diversity, post-synthetic transformations, and mechanistic studies using DFT calculations are the important practical features.
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