Epstein-Barr Virus Seropositivity, Immune Dysregulation, and Mortality in Pediatric Sepsis
免疫失调
败血症
免疫系统
病毒
医学
免疫学
作者
Aditya Sriram,Kate F. Kernan,Yidi Qin,Zachary Aldewereld,Andrew H. Walton,Stephanie S. Cabler,Gregory A. Storch,Valérie Cheynet,Karen Brengel‐Pesce,Scott Canna,Joseph A. Carcillo,Robert A. Berg,Kathleen L. Meert,Murray M. Pollack,Mark W. Hall,Kit Newth,Rick Harrison,Thomas P. Shanley,Kenneth E. Remy,Hyun Jung Park
出处
期刊:JAMA network open [American Medical Association] 日期:2025-08-19卷期号:8 (8): e2527487-e2527487被引量:3
In this cohort study of pediatric sepsis, EBV seropositivity was associated with immune dysregulation and mortality. Further study is warranted to address the possibility that latent EBV infection immune reprogramming poses an important public health problem that contributes to not only chronic disorders of immune dysregulation but also acute disorders of immune dysregulation, such as sepsis.