Palladium-catalyzed enantioselective domino ring-opening/Hiyama coupling of cyclobutanones: development and application to the synthesis of (+)-herbertene-1,14-diol

A palladium-catalyzed enantioselective domino ring-opening/Hiyama coupling of cyclobutanones is reported, providing chiral 1-indanones bearing a versatile alkenyl group.