透明带
细胞生物学
卵母细胞
卵泡发生
卵黄周隙
多晶硅
超微结构
生物
化学
解剖
男科
胚胎
胚胎发生
医学
作者
Daniela Rodler,Tomohiro Sasanami,Fred Sinowatz
出处
期刊:Cells Tissues Organs
[S. Karger AG]
日期:2011-07-19
卷期号:195 (4): 330-339
被引量:22
摘要
The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional matrix and possesses important functions in the fertilization process: it contributes to the binding of avian spermatozoa to the oocyte and induces acrosomal exocytosis. In contrast to the zona pellucida of mammals, the IPVL does not prevent the physiological polyspermy found in birds. Previous studies have shown that in the Japanese quail <i>(Coturnix japonica)</i> at least 5 glycoproteins are constituents of the IPVL (ZP1, ZP2, ZP3, ZP4, and ZPD). In this study, we investigated the spatiotemporal assembly pattern of the IPVL during folliculogenesis using immunohistochemical and ultrastructural methods. The obtained results clearly show that these glycoproteins are incorporated into the IPVL at distinct points during follicular development, supporting the hypothesis that ZP2 and ZP4 form a type of prematrix into which ZP1, ZP3, and ZPD are integrated at a later stage of development.
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