Objective:To observe the curative effect of shockwave lithotripsy under both laparoscope and choledochoscope in the treatment of hepatolithiasis.Methods:A total of 108 patients with hepatolithiasis were randomly divided into an observation group and a control group with 54 cases in each group.The observation group was treated by shockwave lithotripsy under both laparoscope and choledochoscope.The control group was treated by biopsy forceps lithotripsy under both laparoscope and choledochoscope.The successful rates of lithotripsy,stone clearance rates,operation time,perioperative blood loss,and complication rates were compared.Results:The successful rate of lithotripsy and stone clearance rate of the observation group were higher than those of the control group,the operation time of the observation group was shorter than that of the control group,and the perioperative blood loss and complication rate of the observation group were less than those of the control group(P0.05).Conclusion:Shockwave lithotripsy under both laparoscope and choledochoscope in the treatment of hepatolithiasis is an effective operation method,and can improve the success rate of intrahepatic bile duct stones.