Chemical constituents of Mangifera indica leaves (I).

Objective To study the chemical constituents of Mangifera indica leaves.Methods Silica gel,ODS,Sephadex LH-20 column chromatography,and HPLC were used to isolate and purify the constituents,and their structures were identified by physicochemical properties and spectral data.Results Eleven compounds were isolated from 70% ethanol extract,and identified as quercetin-3-O-β-L-rhamnopyranoside(1),hyperin(2),quercetin-3-O-β-glucopyranoside(3),7-O-methylquercetin-3-O-β-L-rhamnopyranoside(4),rhamnetin-3-O-β-D-glucopyranoside(5),amentoflavone(6),mangiferin(7),irisflophenone-3-C-β-glucoside(8),maclurin-3-C-β-glucoside(9),2,4′,6-trihydroxy-4-methoxybenzophenone-2-O-β-glucoside(10),and irisflophenone-3-C-(6-O-p-hydroxybenzoyl)-O-β-glucoside(11),respectively.Conclusion Compounds 4 and 10 are obtained from the plants of Mangifera L.for the first time,and the NMR data of compound 11 is reported for the first time.