Objective: To explore the effect of early enteral nutritional support in acute severe pancreatitis patients.Methods: 180 acute severe patients were randomly divided into three groups: early entera1 nutrition,entera1 nutrition and parenteral nutrition.In different period,these patients' clinicalant biochemical indicators were observed.Results: The enteral nutrition was better than parenteral nutrition,and early enteral nutrition was better than EN.Conclusion: Enteral nutrition is an effective way to cure acute severe pancreatitis,and it should be started as earlier as possible.