Objective:To establish the reference range of serum creatinine which measured by the sarcosine oxidase method among health adults in Pinggu District.Methods: To determine the serum creatinine in 1448 health adults using the sarcosine oxidase method,according to age and gender to divide the data into two groups for statistical analysis. Results: The reference range of serum creatinine in men is 56.8~97.2 μmol/L.In women the figure is 44.0~71.4 μmol/L in the age group of under 30 years old.Moreover,in the age groups for women of 39~59 years and over 60 years the range is 42.2~77.4 μmol/L and 42.8~85.5 μmol/L respectively.Conclusion: Set up the reference range of serum creatinine among health adults in Pinggu District,therefore provides the relevant parameter to diagnosing the related diseases and observing the curative effect.