Ring-opening radical recombination strategy based on benzothiazolium salts: synthesis of 1,4-benzothiazin-3-one derivatives

This work describes a ferrocene- and oxygen-mediated ring-opening radical recombination of benzothiazolium salts, enabling a three-component tandem reaction with anilines and benzaldehydes to rapidly build the 1,4-benzothiazin-3-one skeleton through C-S bond cleavage and sequential formation of C-O, C-N and C-S bonds.