Hydroxyacetophenones: Urinary Metabolites of Ethylbenzene and Acetophenone in the Rabbit

1. From urine of rabbits injected intraperitoneally with ethylbenzene or acetophenone small amounts of ω-hydroxyacetophenone, p-hydroxyacetophenone, and m-hydroxyacetophenone were isolated.2. The implication of the occurrence of ω-hydroxyacetophenone in the oxidative degradation of ethylbenzene and acetophenone is discussed.