Supramolecular-interaction-mediated aggregation of anticarcinogens on triformyl cholic acid-functionalized Fe3O4 nanoparticles and their dual-targeting treatment for liver cancer

Herein, triformyl cholic acid-modified Fe₃O₄ nanoparticles (TCA-MNPs) were first constructed and developed as a novel drug carrier, possessing a high loading capacity, and the synergistic targeted therapy of hepatoma cells in vitro and in vivo.