Analysis of total pancreaticoduodenectomy in 28 patients with pancreatic cancer

Objective To study the clinical outcomes of 28 pancreatic cancer patients who underwent total pancreaticoduodenectomy. Method The clinical data of 28 patients with pancreatic cancer who underwent total pancreaticoduodenectomy from January 2009 to March 2015 were retrospectively analyzed. Results Among the 28 patients, complications occurred in 11 (39.2%) after the operation. There were 7 patient having Grade Ⅱ, 4 Grade Ⅲ complications. No patient died within 30 days after the operation. Follow-up of 25 patients showed a median survival of 13.5 months. There were 24 patients with pancreatic ductal adenocarcinoma, and the median survival was 13 months. Conclusions Total pancreaticoduodenectomy could not improve long-term survival but it decreased postoperative complications and improved postoperative quality of life. In selected patients, total pancreaticoduodenectomy could be a rational option. Key words: Pancreatic cancer; Total pancreaticoduodenectomy; Postoperative complication