Nephrectomy indications of postrenal obstructive non-functioning kidney

Objective To discuss the nephrectomy indications of postrenal obstructive non-functioning kidney.Methods 48 cases of postrenal obstructive non-functioning kidney were analyzed retrospectively.All the case glomerular filtration rate(GFR) of non-functioning kidney were less than 10 ml/min.According to the treatment,the cases were divided into two groups:the first group included 25 cases whose renal was cut off,and the second group included 23 cases with reservation renal.The serum creatinine,ultrasound,IVP,CT + CTU and ECT were performed for each case before operation,and the serum creatinine were also checked with each case after the operation 3 months later.The second group were also performed ultrasound,IVP and ECT.Sixteen cases in second group were done nephrostomy before surgical treatment,and the drainage were observed.Then the surgery were done for removing the obstruction.Results The serum creatinine rise little in first group,and there was no significant differences.The serum creatinine,ultrasound,IVP,and GFR were significantly improved in 21 cases of the reservation renal group.Only 2 cases the hydronephrosis did not improved and develop into pyonephrosis,and had to cut off the kidney eventually.Conclusion The nephrectomy indications of postrenal obstructive non-functioning kidney were complicated.We should take into consideration of the GFR,the thickness of renal cortex,urine volume,urine pH value,urine specific gravity,urine osmotic pressure,renal artery resistive index,infection of urine,the patient age and the opposite side renal compensation. Key words: Non-functioning kidney;  Nephrectomy;  Postrenal obstruction