Open-Label, Single-Arm, Phase II Study of Pembrolizumab Monotherapy as First-Line Therapy in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma.
肾细胞癌
第一行
阿西替尼
泌尿科
一线治疗
作者
David F. McDermott,Jae-Lyun Lee,Marek Ziobro,Cristina Suárez,Przemyslaw Langiewicz,Vsevolod Matveev,Paweł Wiechno,Rustem Gafanov,Piotr Tomczak,Frédéric Pouliot,Frede Donskov,Boris Alekseev,Sang Joon Shin,Georg A. Bjarnason,Daniel Castellano,Rachel Kloss Silverman,Rodolfo F. Perini,Charles Schloss,Michael B. Atkins
出处
期刊:Journal of Clinical Oncology [American Society of Clinical Oncology] 日期:2021-02-02卷期号:39 (9): 1020-1028被引量:36
标识
DOI:10.1200/jco.20.02365
摘要
PURPOSEPembrolizumab, a programmed death 1 inhibitor, demonstrated promising single-agent activity in untreated patients with various cancer types. The phase II KEYNOTE-427 study evaluated efficacy...