[Reliability and validity of the Chinese version on Comprehensive Scores for Financial Toxicity based on the patient-reported outcome measures].

Objective: To evaluate the reliability and validity of the Chinese version on comprehensive scores for financial toxicity (COST), based on the patient-reported outcome measures. Methods: A total of 118 cancer patients were face-to-face interviewed by well-trained investigators. Cronbach's α and Pearson correlation coefficient were used to evaluate reliability. Content validity index (CVI) and exploratory factor analysis (EFA) were used to evaluate the content validity and construct validity, respectively. Results: The Cronbach's α coefficient appeared as 0.889 for the whole questionnaire, with the results of test-retest were between 0.77 and 0.98. Scale-content validity index (S-CVI) appeared as 0.82, with item-content validity index (I-CVI) between 0.83 and 1.00. Two components were extracted from the Exploratory factor analysis, with cumulative rate as 68.04% and loading>0.60 on every item. Conclusion: The Chinese version of COST scale showed high reliability and good validity, thus can be applied to assess the financial situation in cancer patients.目的： 分析中文版经济毒性综合评分量表的信度和效度。 方法： 对118例癌症患者采用面对面问卷调查，间隔2周后采用同一量表选取部分患者复测，利用SPSS 16.0软件统计分析量表的内外部信度、内容和结构效度。Cronbach’s α系数评价量表内部一致性，Pearson相关系数作为重测信度系数评价外在信度，采用内容效度指数方法定量评价内容效度，用探索性因子分析量表的结构效度。 结果： 量表的Cronbach’s α系数为0.889，重测结果的Pearson相关系数为0.77~0.98，差异均有统计学意义（P<0.05）。中文版COST量表内容效度指数为0.82，各条目的内容效度指数为0.83~1.00；探索性因子分析提取2个公因子，其累积贡献率为68.04%，各条目在相应因子上的因子载荷均>0.60。 结论： 中文版经济毒性综合评分量表具有较好的信度和效度，可应用于癌症人群研究。.