Chemistry and Structure-Activity Relationships of Biguanides
化学
计算生物学
生物
作者
E. Prugnard,Michèle Noël
出处
期刊:Handbook of experimental pharmacology日期:1996-01-01卷期号:: 263-285被引量:4
标识
DOI:10.1007/978-3-662-09127-2_10
摘要
In 1878–1879, Rathke obtained a new compound in very low yield via a condensation reaction of thiourea and phosphorus trichloride (which are cyanamide generators) with guanidine.