光老化
氧化应激
皮肤老化
皮肤病科
氧化损伤
紫外线
香烟烟雾
化学
紫外线辐射
紫外线a
医学
毒理
生物化学
生物
材料科学
光电子学
放射化学
出处
期刊:PubMed
日期:2010-08-01
卷期号:145 (4): 445-59
被引量:24
摘要
Our skin suffers from daily exposure to oxidative stress, primarily from exposure to the sun's damaging ultraviolet (UV) rays. This results in the appearance of premature aging. The mechanisms of this photodamage to all layers of the skin by the various wavelengths (UVB and UVA) will be clarified. Recent research further demonstrates a synergistic enhancement of oxidative damage when the skin is exposed to UVA in combination with environmental urban pollutants (including cigarette smoke). The fact that photoaging is largely caused by oxidative damage is confirmed by the demonstration that treatment with topical antioxidants can prevent and even partially reverse UV-induced photodamage. Research substantiating the efficacy of vitamins C and E and of selenium will be reviewed.
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