Postoperative Ileus-Related Morbidity Profile in Patients Treated with Alvimopan after Bowel Resection

Alvimopan 12 mg was associated with reduced POI-related morbidity compared with placebo, without compromising opioid-based analgesia in patients undergoing bowel resection. Relatively low NNTs are clinically meaningful and reinforce the potential benefits of alvimopan for the patient and health care system.