分子印迹聚合物
检出限
表面等离子共振
材料科学
乙二醇二甲基丙烯酸酯
傅里叶变换红外光谱
聚合物
最大残留限量
甲基丙烯酸
接触角
甲基丙烯酸酯
核化学
分子印迹
色谱法
化学工程
分析化学(期刊)
纳米技术
化学
纳米颗粒
选择性
复合材料
单体
有机化学
催化作用
杀虫剂
工程类
农药残留
生物
农学
作者
Önder Kurç,Deniz Türkmen
标识
DOI:10.1007/s13320-022-0658-5
摘要
Abstract Sulfamethoxazole (SMX) is a sulfonamide antibiotic primarily used to treat urinary tract infections and used in veterinary and industrialized husbandry to treat diseases and food additives. Like other antibiotics, SMX is considered as a pollutant in water and food that threaten local life. This study developed a surface plasmon resonance (SPR) sensor chip that is fast, highly selective, and reusable, and requires no pretreatment for detecting SMX. As a receptor, SMX imprinted methacrylic acid-2-hydroxyethyl methacrylate-ethylene glycol dimethacrylate polymer [poly(MAA-HEMA-EGDMA)] was used. The surface of the gold SPR chips was coated with a drop-casting method. The nanofilm coated chips were characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM), ellipsometer, contact angle measurement, and Fourier-transform infrared spectrometry (FTIR). Imprinting factor (IF) was calculated as: Δ R [MIP(molecularly imprinted polymers)]/Δ R [NIP(non-imprinted)]=12/3.5=3.4. Limit of detection (LOD) and limit of quantification (LOQ) values were calculated with 3 s/m and 10 s/m methods, and the results were found to be 0.001 1 µg/L for LOD 0.003 4 µg/L for LOQ. Adsorption studies on both standard SMX solution and commercial milk samples were applied. Also, we investigated the developed chip’s reusability, storability, and selectivity with amoxicillin and cefalexin.
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