A Novel Assent for Synthesis of Pyrazoline Derivatives by adopting Graphene Oxide Nanosheets as carbocatalyst at reflux condition

A novel route was amended for synthesis of 1,3,5-trisustituted pyrazoline derivatives from substituted chalcones and phenyl hydrazine or hydrazine hydrate in ethanol by using Graphene oxide nanosheets as a heterogenous carbocatalyst at reflux condition.The reaction protocol gave 1,3,5-trisubstituted-2-pyrazolines in good yields via a one-pot addition cyclocondensation between aryl hydrazines and chalcones.The catalyst may be reused without showing much loss in the catalytic activity.The synthesized compounds were confirmed by their spectral data analysis.