癌肉瘤
CD8型
医学
胃肠病学
内科学
病理
免疫系统
免疫学
癌
作者
Shusen Chen,Jiamin Zhu,Peng Wang,Dongdong Wan,Xiaojia Cui,Yunzhao Xu,Xing-Song Zhang,Haibin Yin,Xudong Chen,Jing Cai,Xi Yang
标识
DOI:10.1080/07357907.2022.2029474
摘要
We detected PD-L1 and intra-tumoral CD8+ T lymphocytes (CD8+ TIL) in 19 patients with esophageal carcinosarcoma (ECS). The median follow-up period of these patients was 43 months, and the three- and five-year survival rates were 78.9 and 63.2%, respectively. No statistically significant correlation was observed between PD-L1 and CD8+ TIL in sarcomatous components(SC) (r = -0.262, p = 0.279) and epithelial carcinomatous (EC) (r = 0.055, p = 0.824). This study examined the immunological markers in ECS for the first time. PD-L1 is highly expressed in the SC and is associated with a poorer prognosis.
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