A review on nanoparticles categorization, characterization and applications in drug delivery systems

药物输送 纳米技术 药品 生化工程 纳米颗粒 活性成分 计算机科学 步伐 风险分析(工程) 材料科学 药理学 医学 工程类 大地测量学 地理
作者
Shahid Ud Din Wani,Mohammad Ali,Mubashir Hussain Masoodi,Nisar Ahmad Khan,Mohammed Iqbal Zargar,Reyaz Hassan Mir,Suhail Ahmad Mir,Surya Prakash Gautam,H.V. Gangadharappa,Riyaz Ali M. Osmani
出处
期刊:Vibrational Spectroscopy [Elsevier BV]
卷期号:121: 103407-103407 被引量:10
标识
DOI:10.1016/j.vibspec.2022.103407
摘要

Nanoparticles have had significant scientific activity mainly in the field of drug distribution due to their use as a carrier for minute and large-sized molecules over the last few decades. In the present review, we discussed some of the various features of nanoparticle synthesis, classification, the impact of the own features and their use in the distribution of drug entities, and therapeutic effects. Particulate structures such as nano-particles are being utilized as functional methods to modify and also enhance the pharmacokinetics and pharmacodynamics functionality of diverse forms of drug particles. They're employed in vivo to protect medication products from being transported via the body's systemic circulation., limit links of the active pharmaceutical ingredients to selected locations, and also transmit the active pharmaceutical ingredients at a regulated and maintained pace to the operational area. Several different polymers have been used for drug delivery experiments in the development of nanoparticles to maximize clinical gain while minimizing side effects. However, the full application of their capabilities needs to solve several open questions, including significant and long health impacts of nanomaterials and scalable, replicable processing processes, and the long-lasting characteristics of these materials.

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