Early continuous glucose monitoring for predicting remission of type 2 diabetes 1 year after bariatric surgery

Abstract Background Bariatric surgery in obese subjects can result in remission of type 2 diabetes (T2D) at a distant time post-surgery. The aim of our observational prospective single-centre study was to examine glycaemic patterns in adult T2D candidates for bariatric surgery using a continuous glucose monitoring (CGM) sensor for 14 days after surgery to search for indicators predictive of T2D remission 1 year later. Methods Patients underwent CGM preoperatively and for 14 days postoperatively. Thereafter, body weight and glycated haemoglobin (HbA1c) levels were monitored at 3, 6 and 12 months after surgery. Results A total of 31 patients (mean age 47 ± 2 years) were analyzed. After surgery, mean interstitial glucose levels fell rapidly from 157 ± 31 mg/dL preoperatively to 109 ± 35 mg/dL postoperatively (P  Conclusion The use of 14-day postoperative CGM recordings together with presurgical clinical scores can help to predict diabetes remission 1 year after bariatric surgery.