巨蜥
拟南芥
生物
抑制因子
转录因子
隐色素
基因
遗传学
功能(生物学)
抄写(语言学)
生物钟
光周期性
昼夜节律
细胞生物学
植物
神经科学
哲学
突变体
语言学
作者
Mariko Sawa,Dmitri A. Nusinow,Steve A. Kay,Takato Imaizumi
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2007-10-12
卷期号:318 (5848): 261-265
被引量:771
标识
DOI:10.1126/science.1146994
摘要
Precise timing of CONSTANS ( CO ) gene expression is necessary for day-length discrimination for photoperiodic flowering. The FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1), and GIGANTEA (GI) proteins regulate CO transcription in Arabidopsis . We demonstrate that FKF1 and GI proteins form a complex in a blue-light–dependent manner. The timing of this interaction regulates the timing of daytime CO expression. FKF1 function is dependent on GI, which interacts with a CO repressor, CYCLING DOF FACTOR 1 (CDF1), and controls CDF1 stability. GI, FKF1, and CDF1 proteins associate with CO chromatin. Thus, the FKF1-GI complex forms on the CO promoter in late afternoon to regulate CO expression, providing a mechanistic view of how the coincidence of light with circadian timing regulates photoperiodic flowering.
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