Effects of bronchoalvelolar lavage on lung recruited volume and pulmonary mechanic in patients with pulmonary acute respiratory distress syndrome

【Objective】 To access alveolar recruitment and pulmonary mechanic with Bronchoalveolar lavage (BAL) in different positive end-expiratory pressure (PEEP) levels in patients with pulmonary acute respiratory dis-tress syndrome (ARDSp). 【Methods】 Nine ventilated patients satisfying criterial of ARDRp were included in the study group. Recruited volume of three different PEEP levels [5 cmH2O (1 cmH2O=0.098 Kpa),10 cmH2O,15 cmH2O] were measured by pressure-volume cure method before and after BAL and compared . Trending change of different PEEP levels on lung mechanics[peak airway pressure(PIP),Plateau pressure (Pplat),mean airway pressure (Pm) and static compliance(Cst) were compared.【Results】Lung recruited volume elevated when PEEP increased from 5 cmH2O to 15 cmH2O [(35.89±3.93) mL vs.(124.56±9.68)ml vs.(161.70±8.50) mL,P 0.01] before BAL and [(42.27±4.27) mL vs. (139.70±17.59) mL vs. (160.16±9.43) mL,P 0.01] after BAL,but there was no significant dif-ference in trending change between them (F=2.749,P =0.079). There was significant difference of trending change during PIP,Pplat and Pm at different PEEP levels before and after BAL (P 0.05). There was no significant differ-ence in it during Cst (P 0.05).【Conclusions】BAL was not effective to recruited volume with ARDSp,but it re-duced significantly lung airway pressure and improved ventilation.