Analysis of macular thickness in diabetic patients by optical coherence tomography

Objective Investigate and analyze the macular thickness in diabetic patients by optical coherence tomography(OCT) measurements.Methods There were 30 eyes(30 cases) in normal control group,and 90 eyes(30 cases) in diabetic group.The diabetic patients were divided into three groups: non-diabetic retinopathy(NDR),non-proliferative diabetic retinopathy(NPDR) and proliferative diabetic retinopathy(PDR).We observed the different tomographic features of diabetic macula and measured macular thickness.For each eye,nine different sectors were analyzed(central subfield,four parafoveal sectors,and four extrafoveal sectors).All the people had undergone examination of BCVA,slit lamp,ocular fundus,FFA and OCT.Results he average retinal thickness at central subfield(CSF) with 1 mm diameter respectively were NDR Group(225.8±18.0)μm,NPDR Group(246.8±34.2)μm,PDR Group(323.5±92.2)μm,Contral Group(224.8±15.9)μm.There were statistically significant differences in CSF among NPDR group,PDR group and the control eyes(P 0.05).But no significant difference between NDR group and the control eyes.Conclusion OCT can detect macular thickness and structural changes in eyes with DM.It is a useful tool to diagnose and monitor diabetic maculopathy.