Hereditary Fructose Intolerance

HEREDITARY fructose intolerance is an uncommon metabolic disorder, characterized by symptoms of nausea, vomiting, malaise, substernal pain, excessive sweating, tremor, confusion, coma and convulsions, that follows the ingestion of foods containing fructose.1 With continued ingestion of fructose cirrhosis2 3 4 and mental retardation4 , 5 may develop. To date, 23 cases in 14 families1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 have been reported from European clinics. The first description of hereditary fructose intolerance was presented by Chambers and Pratt6 in 1956. In the following year, Froesch et al.5 presented several cases in 1 family, fully described the symptoms of this condition and found that in the patients affected, low levels . . .