An exceptionally stable core–shell MOF/COF bifunctional catalyst for a highly efficient cascade deacetalization–Knoevenagel condensation reaction

A novel strategy has been developed to construct a highly stable core-shell MOF@COF (PCN-222-Co@TpPa-1) bifunctional catalyst through strong π-π stacking interaction. This hybrid material with spatially isolated antagonistic acid-base sites can effectively catalyze the deacetalization-Knoevenagel condensation cascade reaction.