Cyclodextrin-Based Microcapsule Materials - Their Preparation and Physiochemical Properties

Microencapsulation is a technique devoted to entrapping core material inside one or more polymeric coatings. Cyclodextrins (CDs) and its various derivatives are used as functional building blocks because of their unique physical properties. As well CDs possess, the ability to form well-defined host/guest inclusion complexes with lipophilic guests in aqueous solution or polar organic solvents. This review covers literature over the past decade concerning the design of microcapsules containing CDs and their physiochemical properties. Various applications of CD-based microcapsules are anticipated due to their unique surface functionalization, specific morphology, and the occurrence of a complex tertiary structure. The following themes will be addressed in this review: i) the development of CD-based microcapsules, ii) the physiochemical properties of CD-based microcapsules, and iii) the complexation thermodynamics between CDs and target molecules will be examined due to the limited availability of research corresponding to microcapsule results. Keywords: Cyclodextrin, Microcapsules, Microencapsulation, Preparation methods, Physiochemical properties, Encapsulation Methods, Stabilization, lyophilization, Thermodynamic, Ionotropic pre-gelation/ polyelectrolyte