医学
心脏毒性
正电子发射断层摄影术
疾病
分子成像
心肌梗塞
心脏成像
心力衰竭
血管生成
冠状动脉疾病
癌症
内科学
放射科
心脏病学
化疗
生物技术
生物
体内
作者
Zahra Shaghaghi,Fatemeh Jalali Zefrei,Arsalan Salari,Seyed Amineh Hojjati,Seyed Aboozar Fakhr Mousavi,Soghra Farzipour
出处
期刊:Current Radiopharmaceuticals
[Bentham Science]
日期:2023-09-01
卷期号:16 (3): 171-184
标识
DOI:10.2174/1874471016666230228102231
摘要
Cancer treatment has the potential to cause cardiovascular issues and can encourage the appearance of all aspects of cardiac disease, including coronary heart disease, myocardial disease, heart failure, structural heart disease, and rhythm problems. Imaging is required for both diagnostic workup and therapy monitoring for all possible cardiovascular side effects of cancer therapy. Echocardiography is the cardiac imaging gold standard in cardio-oncology. Despite advancements in its use, this method is often not sensitive to early-stage or subclinical impairment. The use of molecular imaging technologies for diagnosing, assessing, and tracking cardiovascular illness as well as for treating, it is fast growing. Molecular imaging techniques using biologically targeted markers are gradually replacing the traditional anatomical or physiological approaches. They offer unique insight into patho-biological processes at the molecular and cellular levels and enable the evaluation and treatment of cardiovascular disease. This review paper will describe molecularbased single-photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging techniques that are now available and in development to assess post-infarction cardiac remodeling. These methods could be used to evaluate important biological processes such as inflammation, angiogenesis, and scar formation.
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