奥拉帕尼
医学
PARP抑制剂
胰腺癌
靶向治疗
合成致死
奥沙利铂
伊立替康
癌症
内科学
癌症研究
聚ADP核糖聚合酶
肿瘤科
DNA修复
结直肠癌
聚合酶
生物化学
化学
基因
作者
Conor Buckley,Eileen M. O’Reilly
标识
DOI:10.1080/17474124.2024.2322648
摘要
There is notable potential for targeted therapies for KRAS-mutated PDAC with opportunity for meaningful benefit for a sizable portion of patients with this disease. Further, emerging approaches are focused on novel immune, tumor microenvironment, and synthetic lethality strategies.
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