肝细胞癌
保健品
小檗碱
医学
内科学
肿瘤科
胃肠病学
传统医学
药理学
病理
作者
Melchiorre Cervello,Giuseppa Augello,Lucio Cocco,Stefano Ratti,Matilde Y. Follo,Alberto M. Martelli,Antonella Cusimano,Giuseppe Montalto,James A. McCubrey
出处
期刊:Advances in biological regulation
日期:2024-04-01
卷期号:: 101032-101032
标识
DOI:10.1016/j.jbior.2024.101032
摘要
Hepatocellular carcinoma (HCC) is a common cancer which unfortunately has poor outcomes. Common anti-cancer treatments such as chemotherapy and targeted therapy have not increased patient survival significantly. A common treatment for HCC patients is transplantation, however, it has limitations and complications. Novel approaches are necessary to more effectively treat HCC patients. Berberine (BBR) is a nutraceutical derived from various fruits and trees, which has been used for centuries in traditional medicine to treat various diseases such as diabetes and inflammation. More recently, the anti-proliferation effects of BBR have been investigated in the treatment of patients with various cancers, especially colorectal cancer, and in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). In this review, we will focus on studies with BBR in liver diseases.
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