Tripleipso-defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols: access to fluoroalkylated orthoestersviaC(sp3)–F bond cleavage

The triple ipso-defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols by C(sp3)-F bond cleavage is reported, delivering various fluoroalkylated orthoesters in high yields. This reaction is transition-metal free and gram-scalable, features mild reaction conditions, and tolerates diverse functional groups.