Synthesis of a Golgi-targeting fluorescent probe for the selective detection of chloride anions

In this paper, we describe the synthesis and properties of a Golgi-targeting fluorescent probe for the selective detection of chloride anions. Specifically, we have synthesized one quaternized quinoline derivative bearing a sulfanilamido group and found that this compound is able to primarily target the Golgi apparatus and detect the changes in the concentration of cellular chloride anions.