Bidirectional mendelian randomization and single-cell sequencing reveal T cell-mediated causal links between COPD and lung adenocarcinoma

This study analyzed the role of CD4 + T cells in COPD and lung adenocarcinoma and found that the CXCR4 gene may affect lung adenocarcinoma development, providing new insights into the link between COPD and lung adenocarcinoma.