诊断准确性
放射科
医学
单光子发射计算机断层摄影术
定量评估
核医学
定量计算机断层扫描
定性分析
定量分析(化学)
病变
医学物理学
定性研究
病理
骨密度
骨质疏松症
社会科学
风险分析(工程)
化学
色谱法
社会学
作者
Mario-Demian Mutuleanu,Diana Păun,Alexandra Maria Lazăr,Cristina Petroiu,Oana Trifănescu,Rodica Maricela Anghel,Mirela Gherghe
出处
期刊:Diagnostics
[MDPI AG]
日期:2023-09-17
卷期号:13 (18): 2971-2971
标识
DOI:10.3390/diagnostics13182971
摘要
(1) Background: Considering the importance that quantitative molecular imaging has gained and the need for objective and reproducible image interpretation, the aim of the present review is to emphasize the benefits of performing a quantitative interpretation of single photon emission computed tomography-computed tomography (SPECT-CT) studies compared to qualitative interpretation methods in bone lesion evaluations while suggesting new directions for research on this topic. (2) Methods: By conducting comprehensive literature research, we performed an analysis of published data regarding the use of quantitative and qualitative SPECT-CT in the evaluation of bone metastases. (3) Results: Several studies have evaluated the diagnostic accuracy of quantitative and qualitative SPECT-CT in differentiating between benign and metastatic bone lesions. We collected the sensitivity and specificity for both quantitative and qualitative SPECT-CT; their values ranged between 74–92% and 81–93% for quantitative bone SPECT-CT and between 60–100% and 41–100% for qualitative bone SPECT-CT. (4) Conclusions: Both qualitative and quantitative SPECT-CT present an increased potential for better differentiating between benign and metastatic bone lesions, with the latter offering additional objective information, thus increasing diagnostic accuracy and enabling the possibility of performing treatment response evaluation through accurate measurements.
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