古代DNA
古生物学
很深的时间
航程(航空)
古地磁
推论
分歧(语言学)
更新世
进化生物学
生物多样性
生物
地球科学
地质学
生态学
计算机科学
人口学
人工智能
人口
语言学
哲学
材料科学
社会学
复合材料
作者
Love Dalén,Peter D. Heintzman,Beth Shapiro
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2023-10-06
卷期号:382 (6666): 48-53
被引量:1
标识
DOI:10.1126/science.adh7943
摘要
Although most ancient DNA studies have focused on the last 50,000 years, paleogenomic approaches can now reach into the early Pleistocene, an epoch of repeated environmental changes that shaped present-day biodiversity. Emerging deep-time genomic transects, including from DNA preserved in sediments, will enable inference of adaptive evolution, discovery of unrecognized species, and exploration of how glaciations, volcanism, and paleomagnetic reversals shaped demography and community composition. In this Review, we explore the state-of-the-art in paleogenomics and discuss key challenges, including technical limitations, evolutionary divergence and associated biases, and the need for more precise dating of remains and sediments. We conclude that with improvements in laboratory and computational methods, the emerging field of deep-time paleogenomics will expand the range of questions addressable using ancient DNA.
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