吲达帕胺
生物等效性
药代动力学
医学
生物利用度
固定剂量组合
药理学
交叉研究
活性代谢物
不利影响
联合疗法
利尿剂
安慰剂
病理
替代医学
作者
Ni Fan,Zhou Gongmin,Wenming Cheng,Yang Jiao,Ruijie Zhang,Chen Yan,Tong Xiangming,Wu Yi
摘要
were 987 and 999 ng/mL, 8059 and 7749 ng/mL h, and 8332 and 8007 ng/mL h, respectively. The corresponding values for indapamide were 27 and 32 ng/mL, 1002 and 1105 ng/mL h, and 1080 and 1172 ng/mL h. No serious adverse events were reported during the study. The combination tablet containing 240 mg of AI and 1.5 mg of indapamide SR met the bioequivalence standards. Additionally, both formulations were tolerated and had good safety profiles in the research.
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