背景(考古学)
神经科学
任务(项目管理)
动态功能连接
脑功能
人脑
大脑活动与冥想
认知
功能连接
大脑定位
功能(生物学)
默认模式网络
心理学
功能磁共振成像
血氧水平依赖性
计算机科学
认知心理学
脑电图
生物
古生物学
管理
进化生物学
经济
作者
Michael Fox,Abraham Z. Snyder,Justin L. Vincent,Maurizio Corbetta,David C. Van Essen,Marcus E. Raichle
标识
DOI:10.1073/pnas.0504136102
摘要
During performance of attention-demanding cognitive tasks, certain regions of the brain routinely increase activity, whereas others routinely decrease activity. In this study, we investigate the extent to which this task-related dichotomy is represented intrinsically in the resting human brain through examination of spontaneous fluctuations in the functional MRI blood oxygen level-dependent signal. We identify two diametrically opposed, widely distributed brain networks on the basis of both spontaneous correlations within each network and anticorrelations between networks. One network consists of regions routinely exhibiting task-related activations and the other of regions routinely exhibiting task-related deactivations. This intrinsic organization, featuring the presence of anticorrelated networks in the absence of overt task performance, provides a critical context in which to understand brain function. We suggest that both task-driven neuronal responses and behavior are reflections of this dynamic, ongoing, functional organization of the brain.
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