沙枣
爸爸
白蜡树
抗氧化剂
传统医学
金黄色葡萄球菌
生物
急性毒性
抗菌活性
植物
化学
作者
Patricia Middleton,Fiona Stewart,Salem Al-Qahtani,Paula Egan,Ciara O’Rourke,Aysha Abdulrahman,Maureen Byres,Moira Middleton,Yashodharan Kumarasamy,Mohammad Shoeb,Lutfun Nahar,Abbas Delazar,Satyajit D. Sarker
出处
期刊:Iranian Journal of Pharmaceutical Research
日期:2005-01-01
卷期号:4 (2): 81-86
被引量:25
标识
DOI:10.22037/ijpr.2010.620
摘要
Alnus glutinosa, Fraxinus excelsior and Papaver rhoeas have long been used in folkloric medicine for the treatment of various ailments. As part of our continuing screening of plant extracts for biological activities, the extracts of A. glutinosa, F. excelsior and P. rhoeas have been screened for their antioxidant and antibacterial activities, as well as their general toxicity towards brine shrimps. Among the extracts, the methanol (MeOH) extract of F. excelsior displayed the highest level of antioxidant activity (RC 50 =1.35x10 -2 mg/mL) and the dichloromethane (DCM) extract of P. rhoeas was the most toxic extract towards brine shrimps (LD 50 =2.4x10 -2 mg/mL). The n-hexane and DCM extracts of F. excelsior and the MeOH extract of A. glutinosa were active (MIC values were within 1.25x10 -1 and 1.00 mg/mL) against all 8 bacterial species tested, including methicillin-resistant Staphylococcus aureus (MRSA).
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