医学
溶栓
头痛
吞咽困难
闭锁综合征
眩晕
构音障碍
基底动脉
闭塞
神经康复
血管痉挛
放射科
蛛网膜下腔出血
外科
心脏病学
康复
物理疗法
心肌梗塞
作者
Heinrich P. Mattle,Marc Ribó,Perttu J. Lindsberg,Wouter J. Schonewille,Gerhard Schroth
出处
期刊:Lancet Neurology
[Elsevier BV]
日期:2011-11-01
卷期号:10 (11): 1002-1014
被引量:479
标识
DOI:10.1016/s1474-4422(11)70229-0
摘要
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.
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