3D bioprinted microneedle patches loaded with gambogic acid-iron-doxorubicin nanozymes for postoperative glioma in situ therapy via ferroptosis synergistic chemosensitization

MNs@GFD integrates localized drug release, BBB bypass, hypoxia relief and ferroptosis-mediated chemosensitization into a single platform, establishing a powerful and clinically translatable postoperative chemotherapeutic strategy against glioma.