Directed Molecular Evolution of Proteins or How to Improve Enzymes for Biocatalysis

List of Contributors. Introduction Evolutionary Biotechnology --From Ideas and Concepts to Experiments and Computer Simulations Using Evolutionary Strategies to Investigate the Structure and Function of Chorismate Mutases Construction of Environmental Libraries for Functional Screening of Enzyme Activity Investigation of Phage Display for the Directed Evolution of Enzymes Directed Evolution of Binding Proteins by Cell Surface Display: Analysis of the Screening Process Advanced Screening Strategies for Biocatalyst Discovery Engineering Protein Evolution Exploring the Diversity of Heme Enzymes through Directed Evolution Directed Evolution as a Means to Create Enantioselective Enzymes for Use in Organic Chemistry Applied Molecular Evolution of Enzymes Involved in Synthesis and Repair of DNA Evolutionary Generation versus Rational Design of Restriction Endonucleases with Novel Specificity Evolutionary Generation of Enzymes with Novel Substrate Specificities. Index.