放射性骨坏死
医学
间充质干细胞
放射治疗
头颈部癌
干细胞
外科
并发症
头颈部
骨科手术
干细胞疗法
病理
生物
遗传学
作者
Ainulakbar Mughal,Merhaba Aftab,Abdul Basit Shah Vardag,Zubair Khan,Hamdan Ahmed Pasha,Muhammad Sohail Awan
标识
DOI:10.47391/jpma.akus-12
摘要
Managing osteoradionecrosis is an integral part of complication management in head and neck cancer patients. While essentially an infection, the management of this complication has a considerable task for head and neck surgeons. While various measures have been discussed for the management, stem cells injection therapy is a potential management option. Mesenchymal stem cell therapy provides the local tissue with growth factors and proliferative cells that can aid a radiated tissue in the healing process. The article intends to review the bedrock of the pathology, ranging from pathophysiological and the epidemiological concerns to sparking a potential discussion on the use of mesenchymal stem cell therapy in osteoradionecrosis of mandible in head and neck cancer surgery and thus the ensuing future of the regenerative medicine. Continued...
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