Multi-omics and Network Pharmacology approaches reveal Gui-Ling-Ji alleviates Oligoasthenoteratozoospermia by regulating arachidonic acid pathway

Gui-Ling-Ji (GLJ) described in the ancient medical book 'Yunji Qijian' is a traditional Chinese medicine formula used to improve male fertility. It is now available for the treatment of oligoasthenoteratozoospermia (OAT). However, the active ingredients and mechanism of GLJ are not clear.