类风湿性关节炎
医学
纳米载体
药品
医疗保健服务
重症监护医学
不利影响
药物输送
关节炎
单克隆抗体
靶向给药
药理学
免疫学
医疗保健
抗体
有机化学
化学
经济
经济增长
作者
Abhishek Verma,Preeti Patel,Waleed H. Almalki,Amirhossein Sahebkar,Preeti Patel,Prashant Kesharwani
标识
DOI:10.2174/0929867331666230815112818
摘要
Morbidity, disability, and healthcare expenses associated with rheumatoid arthritis (RA) impose a considerable health and economical burden on both patients and healthcare systems. This review aimed to examine the pathophysiological aspects of RA that may help design different types of drugs and drug delivery systems. These include monoclonal antibodies, immunoglobulins, tiny chemicals, and transgenes for gene therapy. These novel nanocarrier-based therapies target the underlying biological processes involved in RA while minimizing the systemic adverse effects of drugs.
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