TCF7L2型
基因
基因表达
糖尿病
新陈代谢
生物
细胞生物学
遗传学
内分泌学
基因型
单核苷酸多态性
作者
Joanna Krawczyk,William O’Connor,Pedro Henrique Vendramini,Mareike Schell,Kiran J. Biddinger,Matt Kanke,G. Pengo,Ivana Semova,Tiffany Fougeray,Marcia C. Haigis,Krishna G. Aragam,Wouter H. Lamers,Linus Tsai,Praveen Sethupathy,Sudha B. Biddinger
标识
DOI:10.1016/j.molmet.2025.102208
摘要
Taken together, these data indicate that hepatic TCF7L2 has a secondary role in glycemic control, but a primary role in maintaining transcriptional architecture and glutamine homeostasis.
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