A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration

⁻/⁴⁻ redox probe, offering a non-invasive and highly sensitive alternative to conventional methods. Clinical validation using patient samples demonstrates excellent sensor performance, achieving high specificity and reproducibility. Additionally, a deep learning-assisted data analysis framework is integrated to enhance diagnostic accuracy by filtering out noise, identifying disease progression trends. Furthermore, a wearable mouthguard platform integrating the MIP-based electrode, enabling continuous monitoring of oral inflammation and facilitating early therapeutic intervention is developed. This approach, which combines MIP technology, electrochemical biosensing, wearable healthcare, and AI-driven diagnostics, has the potential to establish a next-generation precision oral health monitoring platform, advancing periodontal disease detection and personalized clinical management.