Factors associated with non-lifting of colorectal mucosal lesions

医学 内镜黏膜下剥离术 病态的 结肠镜检查 纤维化 粘膜下层 粘膜肌层 粘膜切除术 外科 不利影响 内窥镜检查 结直肠癌 内科学 放射科 癌症
作者
Jiang-Ping Yu,Shao-Peng Yang,Rong-Wei Ruan,Sheng-Sen Chen,Yan-Dong Li,Hai-Bin Lou,Shi Wang
出处
期刊:Scandinavian Journal of Gastroenterology [Taylor & Francis]
卷期号:: 1-6
标识
DOI:10.1080/00365521.2022.2133971
摘要

Endoscopic submucosal dissection (ESD) is an effective treatment for colorectal tumors. However, lesions that cannot be lifted after submucosal injection are not indication for ESD. This is because the procedure is difficult, and the lesions are often considered as tumor invasion or submucosal fibrosis. The aims of this study are to evaluate the efficacy and safety of ESD for non-lifting lesions and to analyze the causes of non-lifting phenomenon.This retrospective study included 29 patients with non-lifting colon lesions resected by ESD from February 2018 to September 2021. Cases were observed for demographics, endoscopic findings, treatment outcomes, adverse events and endoscopic follow-up. We studied the pathological features of lesions to explore the reasons for non-lifting.Among 29 cases of non-lifting lesions, 20 lesions (69.0%) were 30 mm in diameter or larger. Most of lesions (96.6%) were non-lifting in center, and only one lesions (3.4%) had non-lifting of one side. The en bloc and curative resection rates of ESD were 100 and 86.2%, respectively. There was one (3.4%) delayed bleeding, no perforations and other complications. No tumor recurrence occurred during the follow-up period. For pathological features, 16 (55.2%) non-lifting lesions had submucosal fibrosis and only 4 cases (13.8%) had deep submucosal invasion. There were 9 cases (31.0%) of non-lifting lesions due to musculo-fibrous of muscularis propria anomaly (MMPA).MMPA is another reason for non-lifting signs besides invasive carcinomas and submucosal fibrosis. ESD should be considered in patients with large non-lifting adenoma instead of surgery.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
luochen完成签到,获得积分10
刚刚
bkagyin应助淡定采纳,获得10
1秒前
1秒前
JamesPei应助王莫为采纳,获得10
1秒前
QING完成签到,获得积分20
2秒前
健脊护柱完成签到 ,获得积分10
2秒前
3秒前
liberation完成签到 ,获得积分10
5秒前
May完成签到,获得积分10
5秒前
平常无颜发布了新的文献求助10
5秒前
6秒前
zhao完成签到 ,获得积分10
7秒前
bkagyin应助jimmy采纳,获得10
7秒前
hkh发布了新的文献求助10
8秒前
ppg完成签到,获得积分10
8秒前
只A不B应助独自面对采纳,获得10
9秒前
wqy完成签到,获得积分10
11秒前
MYMELODY完成签到,获得积分10
11秒前
11秒前
王莫为发布了新的文献求助10
12秒前
PZ完成签到,获得积分10
14秒前
笑的得美完成签到,获得积分10
14秒前
tzy6665完成签到,获得积分10
15秒前
平常无颜完成签到,获得积分10
15秒前
LIXI发布了新的文献求助10
16秒前
yulian完成签到,获得积分10
16秒前
Jasper应助hkh采纳,获得10
17秒前
所所应助荣冥幽采纳,获得10
17秒前
王莫为完成签到,获得积分10
18秒前
19秒前
iNk完成签到,获得积分0
19秒前
20秒前
dyk完成签到,获得积分10
20秒前
南挽完成签到,获得积分10
21秒前
Majoe完成签到,获得积分10
21秒前
CipherSage应助新明采纳,获得10
21秒前
Willow完成签到,获得积分10
22秒前
科研大圣完成签到,获得积分10
22秒前
24秒前
jimmy发布了新的文献求助10
24秒前
高分求助中
Applied Survey Data Analysis (第三版, 2025) 800
Narcissistic Personality Disorder 700
Assessing and Diagnosing Young Children with Neurodevelopmental Disorders (2nd Edition) 700
The Elgar Companion to Consumer Behaviour and the Sustainable Development Goals 540
The Martian climate revisited: atmosphere and environment of a desert planet 500
Images that translate 500
Transnational East Asian Studies 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3843340
求助须知:如何正确求助?哪些是违规求助? 3385634
关于积分的说明 10541427
捐赠科研通 3106276
什么是DOI,文献DOI怎么找? 1710911
邀请新用户注册赠送积分活动 823851
科研通“疑难数据库(出版商)”最低求助积分说明 774313